Spontaneous Tumor Lysis Syndrome in an Infant: A Case Report     

Mamatha T. Shenoy  Benedicta D’Souza  Lalesh Naik Akshatha  Vivian D’Souza  Madan Gopal Rajan 《Indian journal of clinical biochemistry : IJCB》2015,30(3):360-362

Tumor lysis syndrome has been observed in patients with malignancies with high cellular burden and high cell turnover, tumor sensitive to therapy, especially after initiating medical treatment. It very rarely occurs spontaneously. The case described here is of 6 months male infant who presented with fever since 1 month and loose stools associated with blood since 15 days. The laboratory investigations showed lactate dehydrogenase (LDH) of 6,192 IU/L and serum uric acid 18.2 mg/dl along with pancytopenia. The infant presented with electrolyte abnormalities and renal failure.  相似文献   

Age-Related Changes in Soluble Vascular Endothelial Growth Factor Receptor 1 (sVEGFR1) and Receptor 2 (sVEGFR2) in Healthy Japanese Subjects     

Yoshihiro Okamoto  Tomoyo Mita  Testuri Kodama  Yoshimitsu Gotoh  Naoya Fujita  Takashi Fukui  Toshiyuki Masuzawa 《Indian journal of clinical biochemistry : IJCB》2015,30(3):351-356

We measured serum soluble vascular endothelial growth factor receptor 1 (sVEGFR1) and receptor 2 (sVEGFR2) levels in healthy Japanese individuals in order to establish a reference value using a specific ELISA. Significant differences were observed in serum sVEGFR1 and sVEGFR2 levels between children and adults. To demonstrate the usefulness of the reference value for children, we measured serum sVEGFR1 and sVEGFR2 levels in children with diarrhea positive (D+) hemolytic uremic syndrome (HUS) as a preliminary study. Serum sVEGFR2 levels in children with HUS were markedly higher than those in healthy children from the onset of D + HUS. The reference value for healthy children in the present study will allow normal and pathological conditions to be discriminated from each other in future study  相似文献   

Mastery Motivation in Children with Intellectual Disability: Is there Evidence for a Down Syndrome Behavioural Phenotype?     

Linda Gilmore  Monica Cuskelly  Melissa Browning 《International Journal of Disability, Development & Education》2015,62(3):265-275

The main purpose of the current study was to provide empirical evidence to support or refute assumptions of phenotypic deficits in motivation for children with Down syndrome (DS). Children with moderate intellectual disability (MID) associated with etiologies other than DS were recruited in an extension of a previous study that involved children with DS and typically developing children. The participants were 29 children with MID and 33 children with DS who were matched on mental age to 33 typically developing children, aged 3–8 years. Mastery motivation was assessed on task measures of curiosity, preference for challenge and persistence, as well as parental reports. There were no significant group differences on the mastery motivation tasks. Parental ratings of mastery motivation differed, with typically developing children generally being rated more highly than each of the disability groups. The view that motivational deficits are part of the DS behavioural phenotype was not supported.  相似文献   

Revisiting the occupational aspirations and destinations of Anglo-Australian and Chinese-Australian high school students     

Ranbir Singh Malik 《Asia Pacific Journal of Education》2015,35(1):27-39

Evidence from Australia lends support to the “Asian high achieving syndrome” in Chinese-Australian students and “self-deprivation syndrome” in Anglo-Australian students. Applying ethnographic case studies approach for doctoral thesis the author collected data on a longitudinal basis from homes and school of these students. All of these students attended the same school located in a predominantly middle class suburb of Perth Metropolitan area in Western Australia. Chinese-Australian families had settled in Perth from Malaysia, Singapore and Hong Kong, whereas Anglo-Australian families had been residing in Perth for three generations. Impetus to revisit these students (now young adults with their own families) 10 years later came from an urge to test the validity of the prediction the author had made in the concluding chapter of his doctoral thesis. The author had claimed that “if Anglo-Australian parents keep on dwelling in the era of 1950s and 1960s and do not change their laid-back attitude about education, their children could eventually be under-privileged in their own country”. Ten years later, the author undertook a follow-up study on these young adults from six of the eight original families in order to find out their occupational destinations and future aspirations. Data for the follow-up study were collected from these young adults and their parents. These research cases were interviewed twice, each time approximately for two hours and their parents were interviewed once for two to three hours. The purpose of this paper is to report the findings of the follow-up study which reveals a remarkable relationship between the attitude towards schooling and academic performance with their subsequent occupational destination.  相似文献   

Young people with high‐functioning autism and Asperger's syndrome planning for and anticipating the move to college: what supports a positive transition?     

Wendy Mitchell  Bryony Beresford 《British Journal of Special Education》2014,41(2):151-171

For many young people in England, the move into continuing education involves a transfer from the school where they were educated to a further education college. For those with high‐functioning autism or Asperger's syndrome, this can be a challenging process. Past research has demonstrated some of the problems that these young people can encounter. This article by Wendy Mitchell and Bryony Beresford, both based in the Social Policy Research Unit at the University of York, adds to the evidence base by describing how best to support these young people, focusing specifically on ‘young person endorsed’ practice. Data are gleaned from qualitative interviews with 18 young people with high‐functioning autism/Asperger's syndrome. Findings reveal that young people welcomed the involvement of practitioners; however, specific forms of help and knowledge were particularly valued. In addition, it was parents, as opposed to professionals, who typically emerged as the most significant and valued source of support. Implications for practice are discussed, including the support needs of parents.  相似文献   

补充扇贝肽对运动大鼠停训后萎缩骨骼肌细胞Caspase-3活性的影响     

潘小玲  郭振新  庞阳康 《山东体育学院学报》2011,27(7):53-57

目的:通过测试萎缩骨骼肌细胞Caspase-3、SOD活性和MDA含量,观察补充扇贝肽对运动大鼠停训导致骨骼肌萎缩后肌细胞Caspase-3活性及其抗氧化能力的影响,研究扇贝肽对停训后骨骼肌萎缩的干预作用。方法:40只SD雄性大鼠以15 m/min的速度,持续性水平跑台训练30 min开始进行递增负荷运动,运动6 d/周,休息1 d/周,速度递增3 m/min/周,时间递增30 min/周,运动3周后即刻处死10只大鼠为基础对照组,其余大鼠随机分组为补充安慰剂阴性对照组、补充牛乳阳性对照组和补充扇贝肽实验组,30只大鼠左侧后肢实施石膏固定模拟停训模型,并进行扇贝肽补充实验。实验组和对照组所有动物每天分别进行灌胃15%扇贝肽饮料2mL、等量的安慰剂和牛乳。结果:发现补充扇贝肽可显著减低停训后萎缩骨骼肌细胞MDA含量增加,增加SOD活性,提高细胞内抗氧化能力,可显著抑制停训后萎缩骨骼肌细胞Caspase-3的活性,从而抑制骨骼肌收缩蛋白和结构蛋白的降解,促进萎缩骨骼肌的恢复。  相似文献   

不同安静代谢率男子在力竭运动中能量代谢特征的实验研究     

易东平  彭莉  吴景程  曹泽亮 《中国体育科技》2011,47(3)

目的:研究不同安静代谢率的男子在力竭运动中能量代谢和底物代谢的特征及差异.方法:以聚类法将16名受试者分成安静代谢率高、低两组,利用功率自行车进行递增负荷力竭运动,采用气体收集法测定能量代谢结果.结果:1)高、低两组受试者随着负荷的递增,糖消耗量、供能及供能百分比逐渐增大,脂肪消耗量及供能逐渐减少;脂肪消耗量在100W(33%～50%力竭负荷)时最大,分别为7.6 mg/min/kg、6.4 mg/min/kg(P<0.05).2)在中小负荷强度时,高组受试者糖消耗量及供能低于低组,而脂肪消耗量及供能则相反,糖、脂肪消耗量及供能百分比差异显著(P<0.05).3)同级负荷时高组总能量输出低于低组,随着运动负荷递增,脂肪供能下降水平及下降时机有明显差异.结论:在递增负荷至力竭运动中,高、低两组受试者能量代谢特征及变化与运动负荷的递增、身体对能量输出需求一致;高组受试者有氧运动能力相对较强;而低组受试者对糖供能的依赖性较大;高组受试者氧化脂肪的能力更强,能量利用更为经济、有效.  相似文献   

BMI和心肺适能对全代谢综合征男性最大脂代谢水平的影响   总被引：1，自引：0，他引：1  

高峰  崔文丽  焦广发  金凤霞  张静 《中国体育科技》2011,47(3)

目的:探究BMI和心肺适能对全代谢综合征男性最大脂代谢水平的影响.方法:采用CDS代谢综合征诊断标准募集24名全代谢综合征(tMS)男性.血清指标检测采用酶法和放免法.直接测定最大耗氧量和最大有氧功.间接测热法和非连续递增负荷法检测最大脂代谢水平.分别依据BMI、最大耗氧量的平均值将被试分为高,低BMI组,高、低心肺适能组.结果:tMS男性整体最大脂氧化率(MFOR)为151.58±20.64 mg/min,最大脂氧化强度(Fatmax)为28.48±5.98%VO2max,Fatmax相应RER为0.94±0.01;供能交叉点为33.42±6.96%VO2max,心肺适能水平为18.25±2.68 ml/kg/mim;高、低BMI组间心肺适能、MFOR、Fatmax和交叉点均无显著性差异;高、低心肺适能组间MFOR具有非常显著性差异(P<0.01),但BMI、Fatmax和交叉点强度均无显著性差异;tMS男性BMI与MFOR相关不具显著性,心肺适能与MFOR具显著性正相关(r=0.75,P<0.01).结论:全代谢综合征男性最大脂氧化强度处于低有氧强度范围,tMS男性最大脂氧化率受心肺适能水平影响,而BMI对其无显著影响.  相似文献   

运动性疲劳中医症候分型及方剂应用研究   总被引：1，自引：0，他引：1  

刘宇飞  李晓琳 《哈尔滨体育学院学报》2011,29(2):83-85

采用文献资料法对运动性疲劳中医症候分型进行了归纳总结,并在分析中医症候类型各自特点的基础上探讨了运动性疲劳各型方剂应用特点,总结归纳出运动性疲劳的中医用药及组方特点,以期为进一步丰富方剂配伍规律及指导临床正确的辨证论治提供一定理论依据。  相似文献   

早期缩微胶片病害的调查研究     

周亚军  李玉虎  左晨曦  赵艳红 《档案学研究》2011,(5):72-75

通过对馆藏的早期缩微胶片的病害调研,作者发现缩微胶片易出现霉变、“银镜”现象与醋酸综合症等病害,其中醋酸综合症是缩微胶片最严重的病害现象,严重危害其安全,导致大部分缩微胶片濒临自毁.本文介绍了早期缩微胶片病害调研基本情况,提出了缩微胶片病害预防措施.  相似文献